IDENTIFYING MODIFIABLE ASPECTS OF GENE-BY-ENVIRONMENT INTERPLAY IN LATER-LIFE COGNITIVE DECLINE
OUR RESEARCH IN THE NEWS
Kevin Thom's research discussed in The Washington Post here
PAPERS PUBLISHED
- Marees, A.T., Smit, D.J.A., Abdellaoui, A., Nivard, M.G., van den Brink, W., Denys, D., Galama, T.J., Verweij, K.J.H., Derks, E.M. (2020), Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits, Nature Human Behavior, conditionally accepted.
- Faul, J.D., Ware, E.B., Kabeto, M.U., Langa, K.M. (2019), The effect of childhood socioeconomic position and social mobility on cognitive function and change among older adults: A comparison between the United States and England. (Journal of Gerontology – B). Forthcoming
- Fonseca, R., Michaud, P., Galama, T.J. and Kapteyn, A. (2020). Accounting for the Rise of Health Spending and Longevity. Journal of the European Economic Association.
- Barth, D., Papageorge, N. and Thom, K. (2020), Genetic Endowments and Wealth Inequality, Journal of Political Economy. doi: 10.1086/705415
- Papageorge, N. and Thom, K. (2019), Genes, Education, and Labor Market Outcomes: Evidence from the Health and Retirement Study, Journal of the European Economic Association.
- Lourida, I., Hannon, E., Littlejohns, T.J., Langa, K.M., Hyppönen, E., Kuźma, E., and Llewellyn, D.J. (2019), Association of Lifestyle and Genetic Risk With Incidence of Dementia, Journal of the American Medical Association (
- Taylor, J.Y., Ware, E.B., Wright, M.L., Smith, J.A., Kardia, S.L.R. (2019), Using Genetic Burden Scores for Gene-by-Methylation Interaction Analysis on Metabolic Syndrome in African Americans. Biological Research for Nursing, 21(3): 279-285. doi: 10.1177/1099800419828486. Epub 2019 Feb 19. PubMed PMID: 30781968.
- Schmitz, L.L., Gard, A.M., Ware, E.B. (2019), Examining sex differences in pleiotropic effects for depression and smoking using polygenic and gene-region aggregation techniques. American Journal of Medical Genetics, part B, Neuropsychiatric Genetics. doi: 10.1002/ajmg.b.32748. [Epub ahead of print] PubMed PMID: 31219244; NIHMSID:NIHMS1042483.
- Barcellos, S.H., Carvalho, S., Turley, P. (2018), Education can Reduce Health Differences Related to Genetic Risk of Obesity, Proceedings of the National Academy of Sciences (PNAS) of the United States
- Smith, J.A., Kho, M., Zhao, W., Yu, M., Mitchell, C., Faul, J.D. (2018), Genetic effects and gene-by-education interactions on episodic memory performance and decline in an aging population. Social science & medicine (1982). 2018 November 10. PubMed PMID: 30449520; PubMed Central PMCID: PMC6510651; DOI: 10.1016/j.socscimed.2018.11.019.
- Galama, T.J., Lleras-Muney, A. and Van Kippersluis, H. (2018), The Effect of Education on Health and Mortality: A Review of Experimental and Quasi-Experimental Evidence. Oxford Research Encyclopedia of Economics and Finance. Link to working paper. doi:10.1093/acrefore/9780190625979.013.7
- Galama, T.J. and van Kippersluis H. (2018). A Theory of Socioeconomic Disparities in Health Over the Life Cycle. Economic Journal; Link to working paper.
- Kuźma, E., Hannon, E., Zhou, A., Lourida, I., Bethel, A., Levine, D.A., Lunnon, K., Thompson-Coon, J., Hyppönen, E., and Llewellyn, D.(2018), Which risk factors causally influence dementia? A systematic review of Mendelian randomization studies, Journal of Alzheimer’s Disease, 64, pp. 181–193
- Kuźma, E., Lourida, A., Moore, S.F., Levine, D.A., Obioha C. Ukoumunne, O.C., Llewellyn, D.J. (2018). Stroke and dementia risk: A systematic review and meta-analysis. Alzheimers & Dementia, 1-11
WORKING PAPERS / PAPERS SUBMITTED
- Barcellos, S., Carvalho, L. and Turley, P. (2020). Is Education the Great Equalizer? Link to working paper.
- Bakulski, K.M., Vadari, H.S., Faul, J.D., Heeringa, S.G., Kardia, S.L.R., Langa, K.M., Smith, J.A., Manly, J.J., Mitchell, C.M., Benke, K.S., Ware, E.B. (2020). A non-APOE polygenic score for Alzheimer's disease and APOE-ε4 have independent associations with dementia in the Health and Retirement Study (medRxiv). 2020.02.10.20021667; doi: https://doi.org/10.1101/2020.02.10.20021667 (R&R Neurology). Link to working paper.
- Fu, M., Ware, E.B., Faul, J.D., Bakulski, K.M. (2020), Mendelian randomization of smoking behavior on cognitive status among older Americans. (medRxiv) 2019.12.11.19014522; doi: https://doi.org/10.1101/2019.12.11.19014522. Link to working paper.
- Ware, E.B., Faul, J.D., Mitchell, C.M., and Bakulski, K.M. (2019), Considering the APOE locus in polygenic scores for Alzheimer's disease, MedRXiv. Link to working paper. (R&R BMC Genomic Medicine)
- Barcellos, S., Carvalho, L. and Turley, P. (2019). Distributional Effects of Education on Health (May 2019). NBER Working Paper No. w25898.
- Bierut, L., Biroli, P., Galama, T.J., and Thom, K. (2018). Childhood socioeconomic status moderates genetic predisposition for peak smoking. Link to working paper.
- Ware, E.B., Schmitz, L.L., Faul, J.D., Gard, A., Mitchell, C., Smith, J.A., Zhao, W., Weir, D., Kardia, S.L.R. (2019), Heterogeneity in polygenic scores for common human traits. In review.
- Bakulski, K.M., Petrowicz, B., Vadari, H., Faul, J.D., Manly, J., Kardia, S.K., Heeringa, S., Ware, E.B. (2019), Early life exposures and risk for dementia in the Health and Retirement Study. In preparation
- Faul, J.D., Benke, K., Bakulski, K.M., Ware, E.B. (2019), Within and Trans-Racial PGS and Gene-Region Associations. In preparation.
- Brandt, D., Bakulski, K.M., Faul, J.D., Vadari, H.S., Ware, E.B. (2019) Occupational mental and physical work demands associated with cognitive status in older Americans. In preparation.
- Marshall III, W., Ware, E.B., Faul, J.D., Vadari, H.S., Bakulski, K.M. (2019), Family history of Alzheimer’s Disease and cumulative genetic risk in older Americans. In preparation.
- Faul, J.D., Ware, E.B., Kabeto, M.U., Langa, K.M., Llewellyn, D.J., Galama, T. Lifestyle and Genetic Risk: Revisiting the Association with Incident Dementia. In preparation.