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Brain Health Observatory @ USC

BHO Research

BHO

A Real-World Analysis of the Clinical Journey, Diagnosis, and Monitoring Patterns of Patients With Alzheimer Disease by Stage in the United States

September 12, 2025

A Real-World Analysis of the Clinical Journey, Diagnosis, and Monitoring Patterns of Patients With Alzheimer Disease by Stage in the United States

BHO

Prediction of infusion capacity to deliver Alzheimer’s disease treatments in the United States relative to expected demand

August 29, 2025

Prediction of infusion capacity to deliver Alzheimer's disease treatments in the United States relative to expected demand

BHO

A preliminary economic evaluation of a potential program for the primary prevention of Alzheimer’s disease

August 23, 2025

A preliminary economic evaluation of a potential program for the primary prevention of Alzheimer’s disease

BHO

Use of Cognitive Screening among Older Adults Who Care for People with Dementia: A National Survey

August 4, 2025

Use of Cognitive Screening among Older Adults Who Care for People with Dementia: A National Survey

BHO

System readiness and the patient care pathway for Alzheimer’s disease diagnosis and treatment

June 19, 2025

National Library of Medicine

BHO

Estimation of the value-based price of a blood test for Alzheimer’s disease pathology in primary and specialty care in the U.S

June 9, 2025

Estimation of the value-based price of a blood test for Alzheimer's disease pathology in primary and specialty care in the U.S

BHO

The impact of real-world evidence in implementing and optimizing Alzheimer’s disease care

May 9, 2025

The impact of real-world evidence in implementing and optimizing Alzheimer’s disease care

BHO

Measuring time saved in Alzheimer’s disease: What is a meaningful slowing of progression?

April 11, 2025

Measuring time saved in Alzheimer's disease: What is a meaningful slowing of progression?

BHO

Demographic and clinical characteristics of initial patients receiving amyloid-targeting treatments in the United States after regulatory approval

March 21, 2025

BHO

Usage patterns of cognitive assessments during Medicare’s Annual Wellness Visit: A national survey

February 21, 2025

Usage patterns of cognitive assessments during Medicare's Annual Wellness Visit: A national survey

BHO

Effects of the Davos Alzheimer’s Collaborative early detection of cognitive impairment program on clinician attitudes, engagement, and confidence

February 4, 2025

Effects of the Davos Alzheimer's Collaborative early detection of cognitive impairment program on clinician attitudes, engagement, and confidence

BHO

Disparities in Access to Diagnostic Evaluation for Alzheimer’s Disease in Individuals Dually Eligible for Medicare and Medicaid: A Modeling Study

January 24, 2025

Disparities in Access to Diagnostic Evaluation for Alzheimer’s Disease in Individuals Dually Eligible for Medicare and Medicaid: A Modeling Study

BHO

American’s overall and equity-based societal valuation of a disease-modifying Alzheimer’s treatment: Results from a discrete choice experiment

January 1, 2025

The Journal of Prevention of Alzheimer's Disease

BHO

Real-world diagnostic, referral, and treatment patterns in early Alzheimer’s disease among community-based practices in the United States

November 29, 2024

Real-world diagnostic, referral, and treatment patterns in early Alzheimer's disease among community-based practices in the United States

BHO

Expected wait times for access to a disease-modifying Alzheimer’s treatment in England: A modelling study

November 6, 2024

Expected wait times for access to a disease-modifying Alzheimer’s treatment in England: A modelling study

BHO

Current Capacity for Diagnosing Alzheimer’s Disease in Germany and Implications for Wait Times

October 8, 2024

Current Capacity for Diagnosing Alzheimer's Disease in Germany and Implications for Wait Times

BHO

Considerations for widespread implementation of blood‐based biomarkers of Alzheimer’s disease

October 6, 2024

Considerations for widespread implementation of blood‐based biomarkers of Alzheimer's disease

BHO

Recommendations for clinical implementation of blood‐based biomarkers for Alzheimer’s disease

October 1, 2024

Recommendations for clinical implementation of blood‐based biomarkers for Alzheimer's disease

BHO

Estimates of Current Capacity for Diagnosing Alzheimer’s Disease in Sweden and the Need to Expand Specialist Numbers – September 15, 2024

September 15, 2024

Estimates of Current Capacity for Diagnosing Alzheimer's Disease in Sweden - September 15, 2024

BHO

Implications of treatment duration and frequency for value and cost-effective price of Alzheimer treatmentsImplications of treatment duration and frequency for value and cost-effective price of Alzheimer treatments

July 22, 2024

Implications of treatment duration and frequency for value and cost-effective price of Alzheimer treatments

BHO

Acceptable performance of blood biomarker tests of amyloid pathology — recommendations from the Global CEO Initiative on Alzheimer’s Disease

June 12, 2024

Acceptable performance of blood biomarker tests of amyloid pathology — recommendations from the Global CEO Initiative on Alzheimer’s Disease

BHO

Medical Costs and Caregiver Burden of Delivering Disease-Modifying Alzheimer’s Treatments with Different Duration and Route of Administration.

May 7, 2024

Screenshot of paper - Medical Costs and Caregiver Burden of Delivering Disease-Modifying Alzheimer’s Treatments with Different Duration and Route of Administration.

BHO

State Department of Motor Vehicles Reporting Mandates of Dementia Diagnoses and Dementia Underdiagnosis

April 25, 2024

Screenshot of paper - State Department of Motor Vehicles Reporting Mandates of Dementia Diagnoses and Dementia Underdiagnosis

BHO

Economic Impact of Progression from Mild Cognitive Impairment to Alzheimer Disease in the United States

April 2, 2024

Economic Impact of Progression from Mild Cognitive Impairment to Alzheimer Disease in the United States

BHO

Estimated Investment Need to Increase England’s Capacity to Diagnose Eligibility for an Alzheimer’s Treatment to G7 Average Capacity Levels

February 7, 2024

Screenshot of paper - Estimated Investment Need to Increase England’s Capacity to Diagnose Eligibility for an Alzheimer’s Treatment to G7 Average Capacity Levels

BHO

A chance to prevent Alzheimer’s disease sooner than you think

February 2, 2024

Screenshot of paper - A chance to prevent Alzheimer's disease sooner than you think

BHO

Health Economic Considerations in the Deployment of an Alzheimer’s Prevention Therapy

January 30, 2024

Screenshot of paper - Health Economic Considerations in the Deployment of an Alzheimer’s Prevention Therapy

BHO

Focusing on Earlier Management of Alzheimer Disease: Expert Opinion Based on a Modified Nominal Group Technique

January 29, 2024

Screenshot of paper - Focusing on Earlier Management of Alzheimer Disease: Expert Opinion Based on a Modified Nominal Group Technique

BHO

Estimates of Current Capacity for Diagnosing Alzheimer’s Disease in Sweden and the Need to Expand Specialist Numbers – January 11, 2024

January 11, 2024

Estimates of Current Capacity for Diagnosing Alzheimer's Disease in Sweden - January 11, 2024

BHO

Detection Rates of Mild Cognitive Impairment in Primary Care for the United States Medicare Population

January 11, 2024

Screenshot of paper - Detection Rates of Mild Cognitive Impairment in Primary Care for the United States Medicare Population

BHO

Projected Savings to Canadian Provincial Budgets from Reduced Long-Term Care Home Utilization Due to a Disease-Modifying Alzheimer’s Treatment

January 11, 2024

Screenshot of paper - Projected Savings to Canadian Provincial Budgets from Reduced Long-Term Care Home Utilization Due to a Disease-Modifying Alzheimer's Treatment

BHO

The age-specific comorbidity burden of mild cognitive impairment: a US claims database study

December 6, 2023

Screenshot of paper - The age-specific comorbidity burden of mild cognitive impairment: a US claims database study

BHO

Expected wait times for access to a disease-modifying Alzheimer’s treatment in England: A modelling study

November 6, 2023

Screenshot of paper - Expected wait times for access to a disease-modifying Alzheimer's treatment in England: A modelling study

BHO

Detection Rates of Mild Cognitive Impairment in Primary Care for the United States Medicare Population

October 24, 2023

Detection Rates of Mild Cognitive Impairment in Primary Care for the United States Medicare Population

BHO

Estimates of Current Capacity for Diagnosing Alzheimer’s Disease in Sweden and the Need to Expand Specialist Numbers – September 15, 2023

September 15, 2023

Estimates of Current Capacity for Diagnosing Alzheimer's Disease in Sweden and the Need to Expand - September 15, 2023

BHO

A Literature Review on the Burden of Alzheimer’s Disease on Care Partners

September 12, 2023

Screenshot of paper - A Literature Review on the Burden of Alzheimer's Disease on Care Partners

BHO

Expected and diagnosed rates of mild cognitive impairment and dementia in the U.S. Medicare population: observational analysis

July 22, 2023

Screenshot of paper - Expected and diagnosed rates of mild cognitive impairment and dementia in the U.S. Medicare population: observational analysis

BHO

Blood-based biomarkers for Alzheimer’s disease: Current state and future use in a transformed global healthcare landscape

June 8, 2023

Screenshot of paper - Blood-based biomarkers for Alzheimer's disease: Current state and future use in a transformed global healthcare landscape

BHO

Preparedness of China’s health care system to provide access to a disease-modifying Alzheimer’s treatment

June 6, 2023

Screenshot of paper - Preparedness of China's health care system to provide access to a disease-modifying Alzheimer's treatment

BHO

Expanding the use of brief cognitive assessments to detect suspected early-stage cognitive impairment in primary care

April 19, 2023

Screenshot of paper - Expanding the use of brief cognitive assessments to detect suspected early-stage cognitive impairment in primary care

BHO

A framework for addressing Alzheimer’s disease: Without a frame, the work has no aim

December 8, 2022

Screenshot of paper - A framework for addressing Alzheimer's disease: Without a frame, the work has no aim

BHO

Improving community health-care systems’ early detection of cognitive decline and dementia

October 31, 2022

Screenshot of paper - Improving community health-care systems’ early detection of cognitive decline and dementia

BHO

Blood Biomarkers from Research Use to Clinical Practice: What Must Be Done? A Report from the EU/US CTAD Task Force

October 16, 2022

Screenshot of paper - Blood Biomarkers from Research Use to Clinical Practice: What Must Be Done? A Report from the EU/US CTAD Task Force

BHO

Projected Ontario budget savings from reduced long-term care utilization due to a disease-modifying Alzheimer’s treatment

September 14, 2022

Screenshot of paper - Projected Ontario budget savings from reduced long-term care utilization due to a disease-modifying Alzheimer’s treatment

BHO

Preparedness of the Brazilian health-care system to provide access to a disease-modifying Alzheimer’s disease treatment

September 5, 2022

Screenshot of paper - Preparedness of the Brazilian health-care system to provide access to a disease-modifying Alzheimer's disease treatment

BHO

Designing the next-generation clinical carepathway for Alzheimer’s disease

August 19, 2022

Screenshot of paper - Designing the next-generation clinical carepathway for Alzheimer’s disease

BHO

From Trials to Practice: Are We Ready for a Disease-Modifying Treatment?

March 3, 2022

Screenshot of paper - From Trials to Practice: Are We Ready for a Disease-Modifying Treatment?

BHO

Projecting the long-term societal value of a disease-modifying treatment for Alzheimer’s disease in the United States

February 9, 2022

Screenshot of paper - Projecting the long-term societal value of a disease-modifying treatment for Alzheimer's disease in the United States

BHO

Why would Canada have the longest wait times for an Alzheimer’s treatment among the G7 countries?

January 31, 2022

Screenshot of paper - Why would Canada have the longest wait times for an Alzheimer’s treatment among the G7 countries?

BHO

Association of Adverse Events in Opioid Addiction Treatment With Quality Measure for Continuity of Pharmacotherapy

January 25, 2022

Screenshot of paper - Association of Adverse Events in Opioid Addiction Treatment With Quality Measure for Continuity of Pharmacotherapy

BHO

Developing a pathway to support the appropriate, affordable, and widespread use of effective Alzheimer’s prevention drugs

January 18, 2022

Screenshot of paper - Developing a pathway to support the appropriate, affordable, and widespread use of effective Alzheimer's prevention drugs

BHO

Expected wait times for access to a disease-modifying Alzheimer’s treatment in the United States

September 27, 2021

Screenshot of article - Expected wait times for access to a disease-modifying Alzheimer's treatment in the United States

BHO

Memory care approaches to better leverage capacity of dementia specialists: a narrative synthesis

May 10, 2021

Screenshot of article - Memory care approaches to better leverage capacity of dementia specialists: a narrative synthesis

BHO

Is Korea Prepared for an Alzheimer’s Disease-Modifying Therapy? Assessing the Korean Healthcare System Infrastructure and the Effect of Blood-Based Biomarker Tests

February 4, 2021

Screenshot of article - Is Korea Prepared for an Alzheimer’s Disease-Modifying Therapy? Assessing the Korean Healthcare System Infrastructure and the Effect of Blood-Based Biomarker Tests

BHO

Projection of budgetary savings to US state Medicaid programs from reduced nursing home use due to an Alzheimer’s disease treatment

January 1, 2021

screenshot of paper - Projection of budgetary savings to US state Medicaid programs from reduced nursing home use due to an Alzheimer's disease treatment

BHO

Assessing the Preparedness of the Taiwanese Healthcare System Infrastructure for an Alzheimer’s Treatment

January 1, 2021

screenshot of paper - Assessing the Preparedness of the Taiwanese Healthcare System Infrastructure for an Alzheimer’s Treatment

BHO

How Much Value Would a Treatment for Alzheimer’s Disease Offer? Cost-Effectiveness Thresholds for Pricing a Disease-Modifying Therapy

January 1, 2020

screenshot of paper - How Much Value Would a Treatment for Alzheimer's Disease Offer? Cost-Effectiveness Thresholds for Pricing a Disease-Modifying Therapy

BHO

Blood-based biomarkers for Alzheimer’s pathology and the diagnostic process for a disease-modifying treatment: Projecting the impact on the cost and wait times

January 1, 2020

screenshot of paper - Blood-based biomarkers for Alzheimer's pathology and the diagnostic process for a disease-modifying treatment: Projecting the impact on the cost and wait times

BHO

Estimating minimal clinically important differences for two scales in patients with chronic traumatic brain injury

January 1, 2020

screenshot of paper - Estimating minimal clinically important differences for two scales in patients with chronic traumatic brain injury

BHO

Implications of Alzheimer’s Treatment for Organization and Payment of Medical Practices in Canada

January 1, 2020

screenshot of Technical Report - Implications of Alzheimer’s Treatment for Organization and Payment of Medical Practices in Canada

BHO

Implications of Alzheimer’s Treatment for Organization and Payment of Medical Practices in the United States

January 1, 2020

screenshot of article - Implications of Alzheimer’s Treatment for Organization and Payment of Medical Practices in the United States

BHO

Assessing the Preparedness of the Korean Healthcare System Infrastructure for an Alzheimer’s Treatment

January 1, 2020

screenshot of article - Assessing the Preparedness of the Korean Healthcare System Infrastructure for an Alzheimer’s Treatment

BHO

Implications of Alzheimer’s Treatment for OrganizationAnd Payment of Medical Practices in the Eu-5 Countries

January 1, 2020

screenshot of article - Implications of Alzheimer’s Treatment for OrganizationAnd Payment of Medical Practices in the Eu-5 Countries

BHO

Assessing the Preparedness of the Australian Health Care System Infrastructure for an Alzheimer’s Disease-Modifying Therapy

September 21, 2019

Screenshot of paper - Assessing the Preparedness of the Australian Health Care System Infrastructure for an Alzheimer's Disease-Modifying Therapy

BHO

The Potential Emergence of Disease-Modifying Treatments for Alzheimer Disease: The Role of Primary Care in Managing the Patient Journey

January 1, 2019

screenshot of article - The Potential Emergence of Disease-Modifying Treatments for Alzheimer Disease: The Role of Primary Care in Managing the Patient Journey

BHO

The Predicted Long-Term Benefits of Ensuring Timely Treatment and Medication Adherence in Early Schizophrenia

January 1, 2019

screenshot of article - The Predicted Long-Term Benefits of Ensuring Timely Treatment and Medication Adherence in Early Schizophrenia

BHO

Assessing the Preparedness of the Canadian Health Care System Infrastructure for an Alzheimer’s Treatment

January 1, 2019

screenshot of article - Assessing the Preparedness of the Canadian Health Care System Infrastructure for an Alzheimer's Treatment

BHO

Assessing the Preparedness of the Japanese Health Care System Infrastructure for an Alzheimer’s Treatment

January 1, 2019

screenshot of article - Assessing the Preparedness of the Japanese Health Care System Infrastructure for an Alzheimer’s Treatment

BHO

Assessing the Preparedness of the Canadian Health Care System Infrastructure for an Alzheimer’s Treatment

January 1, 2019

screenshot of article - Assessing the Preparedness of the Canadian Health Care System Infrastructure for an Alzheimer's Treatment

BHO

Potential Benefits to Patients and Payers From Increased Measurement of Antipsychotic Plasma Levels in the Management of Schizophrenia

January 1, 2018

screenshot of article - Potential Benefits to Patients and Payers From Increased Measurement of Antipsychotic Plasma Levels in the Management of Schizophrenia

BHO

Simulated long-term outcomes of early use of long-acting injectable antipsychotics in early schizophrenia

January 1, 2018

screenshot of article - Simulated long-term outcomes of early use of long-acting injectable antipsychotics in early schizophrenia

BHO

Evidence for Misspecification of a Nationally Used Quality Measure for Substance Use Treatment

January 1, 2018

screenshot of article - Evidence for Misspecification of a Nationally Used Quality Measure for Substance Use Treatment

BHO

Assessing the Preparedness of the Health Care System Infrastructure in Six European Countries for an Alzheimer’s Treatment

January 1, 2018

screenshot of article - Assessing the Preparedness of the Health Care System Infrastructure in Six European Countries for an Alzheimer's Treatment

BHO

The Role of Antipsychotic Plasma Levels in the Treatment of Schizophrenia

January 1, 2017

screenshot of article - The Role of Antipsychotic Plasma Levels in the Treatment of Schizophrenia

BHO

Improving Antipsychotic Adherence Among Patients With Schizophrenia: Savings for States

January 1, 2015

screenshot of article - Improving Antipsychotic Adherence Among Patients With Schizophrenia: Savings for States